

Bot lane · Patch 26.22 · 330 games together
Vayne and Nautilus: duo build, runes and win rate
- Win rate together47%Vayne alone 49.5% · Nautilus alone 49.3%
- Games together330
- Duo tierC · #330 of duos
- Ahead in gold at 15 min36.9%
- Won in our ladders this week$2.70
From public ranked solo games of this patch, all ranks.
Why this duo works
Together they win 47% of their games, against 49.5% for Vayne and 49.3% for Nautilus with any partner. They lead bot-lane gold at 15 minutes in 36.9% of their games. They are strongest in games over 35 minutes (54.2% win rate).
- Under 25 min39.2%
- 25–35 min47.3%
- Over 35 min54.2%

Vayne
ADC · with Nautilus
Runes
Lethal Tempo
Triumph
Legend: Alacrity
Coup de Grace
Conditioning
Overgrowth
Core items

Doran's Bow 
Blade of The Ruined King 
Guinsoo's Rageblade

Nautilus
Support · with Vayne
Runes
Aftershock
Shield Bash
Bone Plating
Unflinching
Biscuit Delivery
Cosmic Insight
Core items

Celestial Opposition 
Locket of the Iron Solari 
Plated Steelcaps
Lanes this duo wins and loses
No bot lane has played them enough this patch to say.
Other partners
Best supports for Vayne
- Vayne + Lulu47.7%
- Vayne + Lux48.6%
- Vayne + Thresh50%
- Vayne + Leona47.7%
- Vayne + Seraphine51%
Best ADCs for Nautilus
- Kai'Sa + Nautilus49%
- Jhin + Nautilus47.8%
- Miss Fortune + Nautilus52.1%
- Caitlyn + Nautilus46.9%
- Samira + Nautilus52.5%
Players on this duo won $2.70 in Gamercraft ladders this week
Your normal ranked games count. Skill-based: you win on your own play.
Vayne and Nautilus FAQ
Is Vayne and Nautilus a good duo in patch 26.22?
They win 47% of their 330 games together this patch, #330 of all bot lane duos.
What runes should Vayne take with Nautilus?
In this duo most Vayne players take Lethal Tempo, winning 45.9% of their games.
What should Nautilus build with Vayne?
The most played core is Celestial Opposition, Locket of the Iron Solari, Plated Steelcaps, with a 56% win rate.
Which bot lanes beat Vayne and Nautilus?
No bot lane has a clear edge on them this patch.